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Article

The N-glycome regulates the endothelial-to-hematopoietic transition

3 Dec 2020

Abstract excerpt

Sugar code regulates blood stem cells During embryonic development, blood stem cells are derived from vascular endothelial cells that line the walls of developing arteries. The transition from endothelial cells to blood stem cells is highly regulated and restricted to a small portion of endothelial cells during a brief period of time. The mechanisms regulating this transition are also poorly understood. Kasper et...

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PMID: 33273096
DOI: 10.1126/science.aaz2121

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