Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Similar Frequency and Inducibility of Intact Human Immunodeficiency Virus-1 Proviruses in Blood and Lymph Nodes

25 Nov 2020

Abstract excerpt

BACKGROUND: The human immunodeficiency virus (HIV)-1 latent reservoir (LR) in resting CD4+ T cells is a barrier to cure. LR measurements are commonly performed on blood samples and therefore may miss latently infected cells residing in tissues, including lymph nodes. METHODS: We determined the frequency of intact HIV-1 proviruses and proviral inducibility in matched peripheral blood (PB) and lymph node (LN)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV Research and Treatment
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33269401
DOI: 10.1093/infdis/jiaa736

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Similar Frequency and Inducibility of Intact Human Immunodeficiency Virus-1 Proviruses in Blood and Lymph NodesPMID 33269401Read ↗

Blood and Lymph Node Dissemination of Clonal Genome-Intact Human Immunodeficiency Virus 1 DNA Sequences During Suppressive Antiretroviral TherapySemantic proximity Read ↗

Low Inducibility of Latent Human Immunodeficiency Virus Type 1 Proviruses as a Major Barrier to CureSemantic proximity Read ↗

Integrated and Total HIV-1 DNA Predict Ex Vivo Viral OutgrowthSemantic proximity Read ↗

Longitudinal Dynamics of Intact HIV Proviral DNA and Outgrowth Virus Frequencies in a Cohort of Individuals Receiving Antiretroviral TherapySemantic proximity Read ↗

Measuring Human Immunodeficiency Virus Reservoirs: Do We Need to Choose Between Quantity and Quality?Semantic proximity Read ↗

Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNASemantic proximity Read ↗

Persistence of an intact HIV reservoir in phenotypically naive T cells.Semantic proximity Read ↗

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.Semantic proximity Read ↗

Measuring integrated HIV DNA ex vivo and in vitro provides insights about how reservoirs are formed and maintainedSemantic proximity Read ↗

New Frontiers in Measuring and Characterizing the HIV ReservoirSemantic proximity Read ↗

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruptionSemantic proximity Read ↗

Relationship between intact HIV-1 proviruses in circulating CD4 + T cells and rebound viruses emerging during treatment interruptionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.