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Article

Copy neutral loss of heterozygosity (cnLOH) patterns in synchronous colorectal cancer.

European journal of human genetics : EJHG - 1 Apr 2021

Tapial Sandra, García Juan Luis, Corchete Luis, Holowatyj Andreana N, Pérez Jessica, Rueda Daniel, Urioste Miguel, González-Sarmiento Rogelio, Perea José

Abstract excerpt

Copy neutral loss of heterozygosity (cnLOH) is a common event in several human malignancies-positing this as a mechanism of carcinogenesis. However, the role of cnLOH in synchronous colorectal cancer (SCRC), a unique CRC subtype, is not well understood. The aim of this study was to establish a cnLOH profile of SCRC using a single-nucleotide polymorphism array (SNP-A), and to explore associations between cnLOH and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33268847
DOI: 10.1038/s41431-020-00774-w
PMCID: PMC8115567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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