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Article

Molecular basis of weak D expression in the Indian population and report of a novel, predominant variant RHD allele.

Transfusion - 1 Jun 2018

Fichou Yann, Parchure Disha, Gogri Harita, Gopalkrishnan Vidya, Le Maréchal Cédric, Chen Jian-Min, Férec Claude, Madkaikar Manisha, Ghosh Kanjaksha, Kulkarni Swati

Abstract excerpt

BACKGROUND: The Rh blood group system is the most polymorphic system and is implicated in hemolytic transfusion reaction and hemolytic disease of the fetus and newborn. Molecular genetics of the RH genes have been extensively studied in Caucasians, Africans, and East Asians and the variant alleles giving rise to weak and partial D phenotypes have been reported. However, limited genetic studies have been carried...

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Identifiers

PMID: 29479713
DOI: 10.1111/trf.14552

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RHD

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