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Article

DNA damage repair gene mutation testing and genetic counseling in men with/without prostate cancer: a systematic review.

Future oncology (London, England) - 1 Mar 2021

Armstrong Nigel, Quek Ruben Gw, Ryder Steve, Ross Janine, Buksnys Titas, Forbes Carol, Fox Kathleen M, Castro Elena

Abstract excerpt

Background: Ongoing clinical trials are investigating PARP inhibitors to target the DNA damage repair (DDR) pathway in prostate cancer. DDR mutation screening will guide treatment strategy and assess eligibility for clinical trials. Materials & methods: This systematic review estimated the rate of DDR mutation testing or genetic counseling among men with or at risk of prostate cancer. Results: From 6856 records,...

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Identifiers

PMID: 33263430
DOI: 10.2217/fon-2020-0569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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