Article
Germline Testing in Prostate Cancer: When and Who to Test.
Oncology (Williston Park, N.Y.) - 20 Oct 2021
Sokolova Alexandra, Cheng Heather
Abstract excerpt
The results of multiple studies have shown that a substantial proportion of men with advanced prostate cancer carry germline DNA repair mutations. Germline testing in prostate cancer may inform treatment decisions and consideration for clinical trials. There are 2 FDA approved PARP inhibitors (PARPi), olaparib (Lynparza) and rucaparib (Rubraca), for the treatment of advanced prostate cancer with DNA repair...
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