Article
Analysis of the Circulating Tumor Cell Capture Ability of a Slit Filter-Based Method in Comparison to a Selection-Free Method in Multiple Cancer Types.
International journal of molecular sciences - 27 Nov 2020
Takagi Hidenori, Dong Liang, Kuczler Morgan D, Lombardo Kara, Hirai Mitsuharu, Amend Sarah R, Pienta Kenneth J
Abstract excerpt
Circulating tumor cells (CTCs) are a promising biomarker for cancer liquid biopsy. To evaluate the CTC capture bias and detection capability of the slit filter-based CTC isolation platform (CTC-FIND), we prospectively compared it head to head to a selection-free platform (AccuCyte®-CyteFinder® system). We used the two methods to determine the CTC counts, CTC positive rates, CTC size distributions, and CTC...
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