Article
A Novel System to Detect Circulating Tumor Cells Using Two Different Size-selective Microfilters.
Anticancer research - 1 Oct 2020
Sonoda Tomoaki, Yanagitani Noriko, Suga Kanako, Yoshizawa Takahiro, Nishikawa Shingo, Kitazono Satoru, Horiike Atsushi, Shiba Kiyotaka, Ishizuka Tamotsu, Nishio Makoto, Matsusaka Satoshi
Abstract excerpt
BACKGROUND/AIM: Clusters of circulating tumor cells (CTCs) increase metastatic potential compared to single CTC. However, conventional technologies have been unable to generate an accurate analysis of single and cluster CTCs in the peripheral blood. We propose an effective strategy to detect and isolate both single and cluster CTCs using two size-selective microfilters. MATERIALS AND METHODS: Five ml of whole...
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