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Detection of circulating tumor cells: Advances and critical concerns (Review)

29 Mar 2021

Abstract excerpt

Metastasis is the main cause of cancer-related death and the major challenge in cancer treatment. Cancer cells in circulation are termed circulating tumor cells (CTCs). Primary tumor metastasis is likely due to CTCs released into the bloodstream. These CTCs extravasate and form fatal metastases in different organs. Analyses of CTCs are clarifying the biological understanding of metastatic cancers. These data are...

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PMID: 33850563
DOI: 10.3892/ol.2021.12683

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