Article
Calorie restriction during gestation affects ovarian reserve in offspring in the mouse.
Reproduction, fertility, and development - 1 Dec 2020
Zanini Bianka M, Andrade Kelvin R S, Pradiee Jorgea, Veiga Gabriel B, Garcia Driele N, Mondadori Rafael G, Cruz Luís A X, Alvarado-Rincón Joao A, Ramirez Renata P, Saccon Tatiana D, Masternak Michal M, Barros Carlos C, Schneider Augusto
Abstract excerpt
The aim of this study was to investigate the effect of calorie restriction (CR) during pregnancy in mice on metabolism and ovarian function in the offspring. Pregnant female mice were divided into two groups, a control group and a CR group (n=7 in each). Mice in the CR group were fed 50% of the amount consumed by control females from Day 10 of gestation until delivery. After weaning, the offspring received diet...
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