Article
Starvation at birth impairs germ cell cyst breakdown and increases autophagy and apoptosis in mouse oocytes
9 Feb 2017
Abstract excerpt
The female reproductive lifespan is largely determined by the size of primordial follicle pool, which is established following germ cell cyst breakdown around birth. Almost two-third of oocytes are lost during germ cell cysts breakdown, following autophagic and apoptosis mechanisms. To investigate a possible relationship between germ cell cyst breakdown and nutrition supply, we established a starvation model in...
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