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Article

Transgenerational Developmental Programming of Ovarian Reserve

3 Nov 2015

Abstract excerpt

Exposure to an adverse early-life environment leads to long-term health problems, many of which are recapitulated in subsequent generations. The female reproductive tract is particularly sensitive to early-life influences, and plays a pivotal role in programming the conceptus. We examine the influence of suboptimal grandmaternal diet on reproductive potential of granddaughters in the absence of any further...

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PMID: 26525600
DOI: 10.1038/srep16175

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