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Temporal Telomere and DNA Damage Responses in the Space Radiation Environment

25 Nov 2020

Abstract excerpt

Telomeres, repetitive terminal features of chromosomes essential for maintaining genome integrity, shorten with cell division, lifestyle factors and stresses, and environmental exposures, and so they provide a robust biomarker of health, aging, and age-related diseases. We assessed telomere length dynamics (changes over time) in three unrelated astronauts before, during, and after 1-year or 6-month missions...

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PMID: 33242411
DOI: 10.1016/j.celrep.2020.108435

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