Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Longitudinal Epigenetic Aging and Leukocyte Analysis of Simulated Space Travel: The Mars-500 Mission

25 Nov 2020

Abstract excerpt

Astronauts undertaking long-duration space missions may be vulnerable to unique stressors that can impact human aging. Nevertheless, few studies have examined the relationship of mission duration with DNA-methylation-based biomarkers of aging in astronauts. Using data from the six participants of the Mars-500 mission, a high-fidelity 520-day ground simulation experiment, we tested relationships of mission...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Spaceflight effects on biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33242403
DOI: 10.1016/j.celrep.2020.108406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Longitudinal Epigenetic Aging and Leukocyte Analysis of Simulated Space Travel: The Mars-500 MissionPMID 33242403Read ↗

Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflightSemantic proximity Read ↗

Telomeres and aging: on and off the planet!Semantic proximity Read ↗

Microgravity-Induced Immune Plasticity and Temporal Modulation of Gene Networks and T Cell Subsets During the MESSAGE Science Mission in Axiom-3 on the ISSSemantic proximity Read ↗

Assessing Immune Stability in Space: Haematological and T Cell Profiling of Astronauts During the MESSAGE Science Mission in Axiom-3 on the ISSSemantic proximity Read ↗

Telomere Length Dynamics and DNA Damage Responses Associated with Long-Duration SpaceflightSemantic proximity Read ↗

Temporal Telomere and DNA Damage Responses in the Space Radiation EnvironmentSemantic proximity Read ↗

Clonal Hematopoiesis Before, During, and After Human Spaceflight.Semantic proximity Read ↗

Twins, Telomeres, and Aging—in Space!Semantic proximity Read ↗

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflightSemantic proximity Read ↗

Accelerated Hematopoietic Stem Cell Aging in SpaceSemantic proximity Read ↗

Microgravity Remodels Longevity Networks in Astronaut PBMCs: Integrated Findings of Telomere Elongation, DNA Repair Responses, and miRNA SuppressionSemantic proximity Read ↗

The use of DNA methylation clock in aging research.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.