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Article

Global Occurrence of Clinically Relevant Hepatitis B Virus Variants as Found by Analysis of Publicly Available Sequencing Data.

Viruses - 23 Nov 2020

Velkov Stoyan, Protzer Ulrike, Michler Thomas

Abstract excerpt

Several viral factors impact the natural course of hepatitis B virus (HBV) infection, the sensitivity of diagnostic tests, or treatment response to interferon-α and nucleos(t)ide analogues. These factors include the viral genotype and serotype but also mutations affecting the HBV surface antigen, basal core promoter/pre-core region, or reverse transcriptase. However, a comprehensive overview of the distribution...

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PMID: 33238650
DOI: 10.3390/v12111344
PMCID: PMC7700573

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