Article
Hepatitis B virus genotypes: global distribution and clinical importance.
World journal of gastroenterology - 14 May 2014
Sunbul Mustafa
Abstract excerpt
At least 600000 individuals worldwide annually die of hepatitis B virus (HBV)-related diseases, such as chronic hepatitis B (CHB), liver cirrhosis (LC), and hepatocellular carcinoma (HCC). Many viral factors, such as viral load, genotype, and specific viral mutations, are known to affect disease progression. HBV reverse transcriptase does not have a proofreading function, therefore, many HBV genotypes,...
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