Article
Complete characterization of the human ABC gene family.
Journal of bioenergetics and biomembranes - 1 Dec 2001
Dean M, Allikmets R
Abstract excerpt
The human ATP-binding cassette (ABC) transporters comprise a large family of membrane transport proteins and play a vital role in many cellular processes. The genes provide functions as diverse as peptide transport, cholesterol and sterol transport, bile acid, retinoid, and iron transport. In addition some ABC genes play a role as regulatory elements. Many ABC genes play a role in human genetic diseases, and...
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