Mitochondrial metabolism and DNA methylation: a review of the interaction between two genomes.

Abstract excerpt

Mitochondria are controlled by the coordination of two genomes: the mitochondrial and the nuclear DNA. As such, variations in nuclear gene expression as a consequence of mutations and epigenetic modifications can affect mitochondrial functionality. Conversely, the opposite could also be true. However, the relationship between mitochondrial dysfunction and epigenetics, such as nuclear DNA methylation, remains...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carbon
• Share to Citric Acid Cycle
• Share to CpG Islands