Article
Mitochondria in health, aging and diseases: the epigenetic perspective.
Biogerontology - 1 Oct 2015
D'Aquila Patrizia, Bellizzi Dina, Passarino Giuseppe
Abstract excerpt
The rate/quality of human aging and the development/progression of diseases depend on a complex interplay among genetics, epigenetics and environment. In this scenario, mitochondrial function (or dysfunction) and mitochondrial DNA have emerged as major players. This is mainly due to their crucial role in energetic balance, in modulating epigenetic programs and in influencing cell stress response. Moreover, it is...
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