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Article

Genomic characterization of HIV-associated plasmablastic lymphoma identifies pervasive mutations in the JAK-STAT pathway.

Blood cancer discovery - 1 Jul 2020

Liu Zhaoqi, Filip Ioan, Gomez Karen, Engelbrecht Dewaldt, Meer Shabnum, Lalloo Pooja N, Patel Pareen, Perner Yvonne, Zhao Junfei, Wang Jiguang, Pasqualucci Laura, Rabadan Raul, Willem Pascale

Abstract excerpt

Plasmablastic lymphoma (PBL) is an aggressive B-cell non-Hodgkin lymphoma associated with immunodeficiency in the context of Human Immunodeficiency Virus (HIV) infection or iatrogenic immunosuppression. While a rare disease in general, the incidence is dramatically increased in regions of the world with high HIV prevalence. The molecular pathogenesis of this disease is poorly characterized. Here, we defined the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33225311
DOI: 10.1158/2643-3230.BCD-20-0051
PMCID: PMC7679070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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