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Article

Clinical Evaluation of the Polygenetic Background of Blood Pressure in the Population-Based Setting.

Hypertension (Dallas, Tex. : 1979) - 1 Jan 2021

Giontella Alice, Sjögren Marketa, Lotta Luca A, Overton John D, Baras Aris, Minuz Pietro, Fava Cristiano, Melander Olle

Abstract excerpt

The clinical value of the polygenetic component of blood pressure (BP) is commonly questioned. We evaluated a genetic risk score for BP (BP-GRS858), based on the most recently published genome-wide association studies variants that were significantly associated with either systolic BP or diastolic BP, for prediction of hypertension and cardiovascular end points. The genotyping was performed in 2 urban-based...

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Identifiers

PMID: 33222547
DOI: 10.1161/HYPERTENSIONAHA.120.15449
PMCID: PMC7612446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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