Article
Prediction of blood pressure changes over time and incidence of hypertension by a genetic risk score in Swedes.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2013
Fava Cristiano, Sjögren Marketa, Montagnana Martina, Danese Elisa, Almgren Peter, Engström Gunnar, Nilsson Peter, Hedblad Bo, Guidi Gian Cesare, Minuz Pietro, Melander Olle
Abstract excerpt
Recent Genome-Wide Association Studies (GWAS) have pinpointed different single nucleotide polymorphisms consistently associated with blood pressure (BP) and hypertension prevalence. However, little data exist regarding single nucleotide polymorphisms predicting BP variation over time and hypertension incidence. The aim of this study was to confirm the association of a genetic risk score (GRS), based on 29...
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