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Clinical Characteristics, Treatments, and Concurrent Mutations in Non-Small Cell Lung Cancer Patients With NF1 Mutations.

Clinical lung cancer - 1 Jan 2021

Bowman Lee, Tiu Ramon, Smyth Emily Nash, Willard Melinda Dale, Li Li, Beyrer Julie, Han Yimei, Singh Ambrish

Abstract excerpt

OBJECTIVES: Metastatic non-small cell lung cancer (mNSCLC) is characterized by complex genomic alterations. NF1 mutations may confer distinct clinical characteristics within NSCLC, and real-world evidence on concurrent mutations, treatment patterns, and health outcomes is lacking. MATERIALS AND METHODS: This retrospective study was performed in patients with mNSCLC treated in the Flatiron Health network who...

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PMID: 33221173
DOI: 10.1016/j.cllc.2020.09.011

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