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Article

Lung-MAP Next-Generation Sequencing Analysis of Advanced Squamous Cell Lung Cancers (SWOG S1400).

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Dec 2024

Kozono David, Hua Xing, Wu Michael C, Tolba Khaled A, Waqar Saiama N, Dragnev Konstantin H, Cheng Haiying, Hirsch Fred R, Mack Philip C, Gray Jhanelle E, Kelly Karen, Borghaei Hossein, Herbst Roy S, Gandara David R, Redman Mary W

Abstract excerpt

INTRODUCTION: Squamous cell cancer (SqCC) is a lung cancer subtype with few targeted therapy options. Molecular characterization, that is, by next-generation sequencing (NGS), is needed to identify potential targets. Lung Cancer Master Protocol Southwest Oncology Group S1400 enrolled patients with previously treated stage IV or recurrent SqCC to assess NGS biomarkers for therapeutic sub-studies. METHODS: Tumors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39111731
DOI: 10.1016/j.jtho.2024.07.024
PMCID: PMC11625613

Genes

PARP4
KEAP1
NFE2L2
CDKN2A
RB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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