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Prognostic features and comprehensive genomic analysis of NF1 mutations in EGFR mutant lung cancer patients.

Cancer medicine - 1 Jan 2023

Tian Hong-Xia, Chen Zhi-Hong, Jie Guang-Ling, Wang Zhen, Yan Hong-Hong, Wu Si-Pei, Zhang Shui-Lian, Lu Dan-Xia, Zhang Xu-Chao, Wu Yi-Long

Abstract excerpt

OBJECTIVE: NF1 is a tumor suppressor gene that encodes the neurofibromin protein and negatively regulates Ras signaling. This study was aimed to investigate the molecular, clinical characteristics, and prognostic features of NF1 gene in EGFR mutant lung cancer patients. METHOD: The next-generation sequencing (NGS) was used to analyze the data from lung cancer patients in the Guangdong Lung Cancer Institute (GLCI)...

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Identifiers

PMID: 35702826
DOI: 10.1002/cam4.4925
PMCID: PMC9844590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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