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Article

Mucin mutations and aberrant expression are associated with the pathogenesis of immune thrombocytopenia.

Thrombosis research - 1 Oct 2020

Zhu Jing-Jing, Yuan Dai, Sun Rui-Jie, Liu Shu-Yan, Shan Ning-Ning

Abstract excerpt

PURPOSE: Primary immune thrombocytopenia (ITP) is an acquired autoimmune disease of unknown aetiology. In this study, we aimed to identify the mutations and aberrant expression of mucins associated with ITP pathogenesis. METHODS: First, we investigated the DNA mutation profile of bone marrow samples from patients with ITP (n = 20) by using next-generation sequencing (NGS). In addition, MUC3A, MUC5B and MUC6 were...

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Identifiers

PMID: 33213847
DOI: 10.1016/j.thromres.2020.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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