Article

Gene mutations in members of the PI3K/Akt signalling pathway are related to immune thrombocytopenia pathogenesis

2020-11-17

Abstract excerpt

<h4>Purpose</h4> Immune thrombocytopenic (ITP) is an autoimmune bleeding disease with genetic susceptibility. In this research, we conducted an in-depth genomic analysis of a cohort of patients and elucidated the molecular features associated with the pathogenesis of ITP. <h4>Method</h4> High-molecular-weight genomic DNA was extracted from freshly frozen bone marrow blood mononuclear cells (BMBMCs) from 20 activ...

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Literature Corpus work: 9f31d9ed-827c-5b80-8eb8-2ff4a21c4295
DOI: 10.1101/2020.11.16.385963

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