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Article

DCC gene network in the prefrontal cortex is associated with total brain volume in childhood.

Journal of psychiatry & neuroscience : JPN - 18 Nov 2020

Morgunova Alice, Pokhvisneva Irina, Nolvi Saara, Entringer Sonja, Wadhwa Pathik, Gilmore John, Styner Martin, Buss Claudia, Sassi Roberto Britto, Hall Geoffrey B C, O'Donnell Kieran J, Meaney Michael J, Silveira Patricia P, Flores Cecilia A

Abstract excerpt

BACKGROUND: Genetic variation in the guidance cue DCC gene is linked to psychopathologies involving dysfunction in the prefrontal cortex. We created an expression-based polygenic risk score (ePRS) based on the DCC coexpression gene network in the prefrontal cortex, hypothesizing that it would be associated with individual differences in total brain volume. METHODS: We filtered single nucleotide polymorphisms...

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Identifiers

PMID: 33206040
DOI: 10.1503/jpn.200081
PMCID: PMC7955849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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