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Zika Virus-Encoded NS2A and NS4A Strongly Downregulate NF-κB Promoter Activity

17 Nov 2020

Abstract excerpt

Since Zika virus (ZIKV) was first detected in Uganda in 1947, serious outbreaks have occurred globally in Yap Island, French Polynesia and Brazil. Even though the number of infections and spread of ZIKV have risen sharply, the pathogenesis and replication mechanisms of ZIKV have not been well studied. ZIKV, a recently highlighted Flavivirus, is a mosquito-borne emerging virus causing microcephaly and the...

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PMID: 33203823
DOI: 10.4014/jmb.2011.11003

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