Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct and Indirect Inhibition of Salmonella Peptide Deformylase by Nitric Oxide.

mBio - 17 Nov 2020

Singhal Anshika, Fang Ferric C

Abstract excerpt

Salmonella enterica serovar Typhimurium is an intracellular pathogen that elicits nitric oxide (NO·) production by host macrophages. NO· is a potent antimicrobial mediator with diverse targets, including protein thiols and metal centers. The mobilization of zinc from metalloproteins by NO· increases the availability of free intracellular zinc, which is detrimental to bacterial cells, but the precise mechanism of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amidohydrolases
Share to Anti-Infective Agents
Share to Homeostasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metalloproteins

Share to Nitric Oxide

Share to Salmonella typhimurium

Source

Open in PubMed Open full text

Identifiers

PMID: 33203749
DOI: 10.1128/mBio.01383-20
PMCID: PMC7683392

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct and Indirect Inhibition of Salmonella Peptide Deformylase by Nitric Oxide.PMID 33203749Read ↗

Manganese import protects Salmonella enterica serovar Typhimurium against nitrosative stress.Semantic proximity Read ↗

An opportunistic pathogen under stress: how Group B <i>Streptococcus</i> responds to cytotoxic reactive species and conditions of metal ion imbalance to surviveSemantic proximity Read ↗

A Novel Antimicrobial Approach Based on the Inhibition of Zinc Uptake in Salmonella EntericaSemantic proximity Read ↗

Nitric Oxide restricts iron availability and induces quorum sensing in Streptococcus pyogenesSemantic proximity Read ↗

Zinc Homeostasis at the Bacteria/Host Interface—From Coordination Chemistry to Nutritional ImmunitySemantic proximity Read ↗

Nitric oxide releases intracellular zinc from prokaryotic metallothionein in Escherichia coli.Semantic proximity Read ↗

Zinc limitation triggers anticipatory adaptations in Mycobacterium tuberculosisSemantic proximity Read ↗

New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide.Semantic proximity Read ↗

Magnesium homeostasis protects Salmonella against nitrooxidative stress.Semantic proximity Read ↗

Haem oxygenase limits Mycobacterium marinum infection‐induced detrimental ferrostatin‐sensitive cell death in zebrafishSemantic proximity Read ↗

Dr. NO and Mr. Toxic – the versatile role of nitric oxideSemantic proximity Read ↗

Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.