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Nitric Oxide restricts iron availability and induces quorum sensing in Streptococcus pyogenes

4 Jun 2025

Abstract excerpt

Nitric oxide (NO) is a free radical signaling molecule with multiple biological functions. As part of the innate immune system, NO has antimicrobial properties playing an important role in host defense. Mechanisms of NO cytotoxicity result from its ability to bind metals and inhibit enzyme function or by increasing nitrosative and oxidative stress within cells. One of the primary biological targets of NO is the...

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PMID: 40483894
DOI: 10.1016/j.redox.2025.103699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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