Article
Manganese import protects Salmonella enterica serovar Typhimurium against nitrosative stress.
Metallomics : integrated biometal science - 1 Nov 2020
Yousuf Shehla, Karlinsey Joyce E, Neville Stephanie L, McDevitt Christopher A, Libby Stephen J, Fang Ferric C, Frawley Elaine R
Abstract excerpt
Nitric oxide (NO˙) is a radical molecule produced by mammalian phagocytic cells as part of the innate immune response to bacterial pathogens. It exerts its antimicrobial activity in part by impairing the function of metalloproteins, particularly those containing iron and zinc cofactors. The pathogenic Gram-negative bacterium Salmonella enterica serovar typhimurium undergoes dynamic changes in its cellular content...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
