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Article

Nitric oxide releases intracellular zinc from prokaryotic metallothionein in Escherichia coli.

FEMS microbiology letters - 16 Jul 2002

Binet Marie R B, Cruz-Ramos Hugo, Laver Jay, Hughes Martin N, Poole Robert K

Abstract excerpt

Nitric oxide (NO) has a broad spectrum of signalling and regulatory functions and multiple molecular targets. Recently, the intrabacterial toxicity of NO and mechanisms for NO resistance have been intensively investigated. Here we report for the first time that NO elicits release of zinc from a bacterial protein. Using the zinc-responsive expression of zntA (encoding a Zn-exporting P-type ATPase) fused to lacZ,...

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PMID: 12127498
DOI: 10.1111/j.1574-6968.2002.tb11295.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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