Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Expression Profiles of ADME Genes in Human Cancers and Their Associations with Clinical Outcomes

13 Nov 2020

Abstract excerpt

ADME genes are a group of genes that are involved in drug absorption, distribution, metabolism, and excretion (ADME). The expression profiles of ADME genes within tumours is proposed to impact on cancer patient survival; however, this has not been systematically examined. In this study, our comprehensive analyses of pan-cancer datasets from the Cancer Genome Atlas (TCGA) revealed differential intratumoral...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Epigenetics and DNA Methylation
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33202946
DOI: 10.3390/cancers12113369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Expression Profiles of ADME Genes in Human Cancers and Their Associations with Clinical OutcomesPMID 33202946Read ↗

Development and Validation of an ADME-Related Gene Signature for Survival, Treatment Outcome and Immune Cell Infiltration in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver CohortSemantic proximity Read ↗

Establishment of non-small-cell lung cancer risk prediction model based on prognosis-associated ADME genes.Semantic proximity Read ↗

ADME gene-driven prognostic model for bladder cancer: a breakthrough in predicting survival and personalized treatmentSemantic proximity Read ↗

Pan-cancer single-cell landscape of drug-metabolizing enzyme genesSemantic proximity Read ↗

Comprehensive pan-cancer analysis: essential role of ABCB family genes in cancerSemantic proximity Read ↗

DNA Methylation of ADME GenesSemantic proximity Read ↗

Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver.Semantic proximity Read ↗

Novel ‘housekeeping’ genes and an unusually heterogeneous distribution of transporter expression profiles in human tissues and cell lines, assessed using the Gini coefficientSemantic proximity Read ↗

Impact of Individual Factors on DNA Methylation of ADME Genes: A Systematic ReviewSemantic proximity Read ↗

Tumoral expression of drug and xenobiotic metabolizing enzymes in breast cancer patients of different ethnicities with implications to personalized medicine.Semantic proximity Read ↗

Characterization of ADME gene variation in 21 populations by exome sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.