Article
Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk.
Cancer medicine - 1 Dec 2020
Zhao Lingling, Liu Hongliang, Luo Sheng, Moorman Patricia G, Walsh Kyle M, Li Wei, Wei Qingyi
Abstract excerpt
Because the cadherin-mediated signaling pathway promotes cancer progression, we assessed associations between genetic variants in 109 cadherin-related genes and risk of pancreatic cancer (PanC) by using genotyping data from publically available genome-wide association studies (GWAS) datasets comprising 15,423 individuals of European ancestry. After initial single-locus analyses and subsequent meta-analysis with...
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