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Article

Psychosis‐Like Behavior and Hyperdopaminergic Dysregulation in Human α‐Synuclein BAC Transgenic Rats

17 Nov 2020

Abstract excerpt

BACKGROUND: Parkinson's disease psychosis is a prevalent yet underreported and understudied nonmotor manifestation of Parkinson's disease and, arguably, the most debilitating. It is unknown if α-synuclein plays a role in psychosis, and if so, this endophenotype may be crucial for elucidating the neurodegenerative process. OBJECTIVES: We sought to dissect the underlying neurobiology of novelty-induced...

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PMID: 33200461
DOI: 10.1002/mds.28383

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