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Article

Critical roles of FAM134B in ER-phagy and diseases

16 Nov 2020

Abstract excerpt

FAM134B (also called JK-1, RETREG1), a member of the family with sequence similarity 134, was originally discovered as an oncogene in esophageal squamous cell carcinoma. However, its most famous function is that of an ER-phagy-regulating receptor. Over the decades, the powerful biological functions of FAM134B were gradually revealed. Overwhelming evidence indicates that its dysfunction is related to...

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PMID: 33199694
DOI: 10.1038/s41419-020-03195-1

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