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Article

Identification of Novel FAM134B (JK1) Mutations in Oesophageal Squamous Cell Carcinoma.

Scientific reports - 4 Jul 2016

Haque Md Hakimul, Gopalan Vinod, Chan Kwok-Wah, Shiddiky Muhammad J A, Smith Robert Anthony, Lam Alfred King-Yin

Abstract excerpt

Mutation of FAM134B (Family with Sequence Similarity 134, Member B) leading to loss of function of its encoded Golgi protein and has been reported induce apoptosis in neurological disorders. FAM134B mutation is still unexplored in cancer. Herein, we studied the DNA copy number variation and novel mutation sites of FAM134B in a large cohort of freshly collected oesophageal squamous cell carcinoma (ESCC) tissue...

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Share to Carcinoma, Squamous Cell
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27373372
DOI: 10.1038/srep29173
PMCID: PMC4931577

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