Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2, ACE2 expression, and systemic organ invasion

4 Dec 2020

Abstract excerpt

A novel coronavirus disease, COVID-19, has created a global pandemic in 2020, posing an enormous challenge to healthcare systems and affected communities. COVID-19 is caused by severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) that manifests as bronchitis, pneumonia, or a severe respiratory illness. SARS-CoV-2 infects human cells via binding a "spike" protein on its surface to angiotensin-converting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to COVID-19 Impact on Reproduction
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33275540
DOI: 10.1152/physiolgenomics.00087.2020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2, ACE2 expression, and systemic organ invasionPMID 33275540Read ↗

ACE2 partially dictates the host range and tropism of SARS-CoV-2Semantic proximity Read ↗

A Closer Look at ACE2 Signaling Pathway and Processing during COVID-19 Infection: Identifying Possible TargetsSemantic proximity Read ↗

ACE2: Its potential role and regulation in severe acute respiratory syndrome and COVID‐19Semantic proximity Read ↗

The protein expression profile of ACE2 in human tissuesSemantic proximity Read ↗

A computational and bioinformatic analysis of ACE2: an elucidation of its dual role in COVID-19 pathology and finding its associated partners as potential therapeutic targetsSemantic proximity Read ↗

The scRNA-seq Expression Profiling of the Receptor ACE2 and the Cellular Protease TMPRSS2 Reveals Human Organs Susceptible to SARS-CoV-2 Infection.Semantic proximity Read ↗

Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemicSemantic proximity Read ↗

Interaction of SARS-CoV-2 and Other Coronavirus With ACE (Angiotensin-Converting Enzyme)-2 as Their Main ReceptorSemantic proximity Read ↗

SARS‐CoV ‐2 multifaceted interaction with the human host. Part II : Innate immunity response, immunopathology, and epigeneticsSemantic proximity Read ↗

Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implicationsSemantic proximity Read ↗

ACE2 Expression Is Increased in the Lungs of Patients With Comorbidities Associated With Severe COVID-19Semantic proximity Read ↗

Factors regulating dynamics of angiotensin-converting enzyme-2 (ACE2), the gateway of SARS-CoV-2: Epigenetic modifications and therapeutic interventions by epidrugsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.