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Integration of transcriptome and cistrome analysis identifies RUNX1-target genes involved in pancreatic cancer proliferation

1 Nov 2020

Abstract excerpt

The extremely high proliferation rate of tumor cells contributes to pancreatic cancer (PC) progression. Runt-related transcription factor 1(RUNX1), a key factor in hematopoiesis that was correlated with tumor progression. However, the role of RUNX1 in PC proliferation was still unclear. We found that RUNX1 was significantly upregulated in PC tissues and its expression was negatively associated with prognosis of...

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PMID: 33189780
DOI: 10.1016/j.ygeno.2020.11.010

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