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Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway

20 Nov 2019

Abstract excerpt

BACKGROUND: Accumulation evidence indicates the vital role of long non-coding RNAs (lncRNAs) in tumorigenesis and the progression of malignant tumors, including pancreatic cancer (PC). However, the role and the molecular mechanism of long non-coding RNA 00976 is unclear in pancreatic cancer. METHODS: In situ hybridization (ISH) and qRT-PCR was performed to investigate the association between linc00976 expression...

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PMID: 31747939
DOI: 10.1186/s13046-019-1388-4

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