Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma

13 Nov 2020

Abstract excerpt

There is a life-long relationship between rhinovirus (RV) infection and the development and clinical manifestations of asthma. In this study we demonstrate that cultured primary bronchial epithelial cells from adults with asthma (n = 9) show different transcriptional and chromatin responses to RV infection compared to those without asthma (n = 9). Both the number and magnitude of transcriptional and chromatin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to IL-33, ST2, and ILC Pathways
Share to Immune Response and Inflammation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33188283
DOI: 10.1038/s42003-020-01411-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthmaPMID 33188283Read ↗

Rhinovirus infection of airway epithelial cells uncovers the non-ciliated subset as a likely driver of genetic susceptibility to childhood-onset asthmaSemantic proximity Read ↗

Rhinovirus infection of airway epithelial cells uncovers the non-ciliated subset as a likely driver of genetic risk to childhood-onset asthma.Semantic proximity Read ↗

Epithelial cell responses to rhinovirus identify an early-life-onset asthma phenotype in adults.Semantic proximity Read ↗

Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthmaSemantic proximity Read ↗

Missing regulatory effects and viral triggers explored for childhood-onset asthma.Semantic proximity Read ↗

Rhinovirus-induced epithelial RIG-I inflammasome activation suppresses antiviral immunity and promotes inflammatory responses in virus-induced asthma exacerbations and COVID-19Semantic proximity Read ↗

Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute WheezingSemantic proximity Read ↗

Airway IRF7 <sup>hi</sup> versus IRF7 <sup>lo</sup> molecular response patterns determine clinical phenotypes in children with acute wheezingSemantic proximity Read ↗

Rhinovirus Infection Drives Complex Host Airway Molecular Responses in Children With Cystic FibrosisSemantic proximity Read ↗

Multi-omics co-localization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locusSemantic proximity Read ↗

Analysis of Exosomal MicroRNA Dynamics in Response to Rhinovirus Challenge in a Longitudinal Case-Control Study of AsthmaSemantic proximity Read ↗

Phenotypic Responses of Differentiated Asthmatic Human Airway Epithelial Cultures to RhinovirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.