Article
Phenotypic Responses of Differentiated Asthmatic Human Airway Epithelial Cultures to Rhinovirus
23 Feb 2015
Abstract excerpt
OBJECTIVES: Human airway epithelial cells are the principal target of human rhinovirus (HRV), a common cold pathogen that triggers the majority of asthma exacerbations. The objectives of this study were 1) to evaluate an in vitro air liquid interface cultured human airway epithelial cell model for HRV infection, and 2) to identify gene expression patterns associated with asthma intrinsically and/or after HRV...
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