Article
Rs-1884444 G/T variant in IL-23 receptor is likely to modify risk of bladder urothelial carcinoma by regulating IL-23/IL-17 inflammatory pathway.
Cytokine - 1 Feb 2021
El-Gedamy Mohammed, El-Khayat Zakaria, Abol-Enein Hassan, El-Said Afaf, El-Nahrery Eslam
Abstract excerpt
Bladder urothelial carcinoma (BUC) is a chronic relapsing urological malignancy, which poses a serious threat to human life. Non-resolving chronic-inflammation at the neoplastic site is associated consistently with inducing tumor-progression and poor patient outcomes. Interleukin 23 receptor (IL-23R) is a key element in T-helper 17 cell-mediated inflammatory process, that plays a critical role in orchestrating...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.