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Article

Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity.

Structure (London, England : 1993) - 1 Mar 2006

Ehrensberger Andreas H, Elling Robert A, Wilson David K

Abstract excerpt

Xylitol dehydrogenase (XDH) is one of several enzymes responsible for assimilating xylose into eukaryotic metabolism and is useful for fermentation of xylose contained in agricultural byproducts to produce ethanol. For efficient xylose utilization at high flux rates, cosubstrates should be recycled between the NAD+-specific XDH and the NADPH-preferring xylose reductase, another enzyme in the pathway. To...

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Identifiers

PMID: 16531240
DOI: 10.1016/j.str.2005.11.016

Genes

XDH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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