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A Lipidomic Signature Complements Stemness Features Acquisition in Liver Cancer Cells

10 Nov 2020

Abstract excerpt

Lipid catabolism and anabolism changes play a role in stemness acquisition by cancer cells, and cancer stem cells (CSCs) are particularly dependent on the activity of the enzymes involved in these processes. Lipidomic changes could play a role in CSCs' ability to cause disease relapse and chemoresistance. The exploration of lipid composition and metabolism changes in CSCs in the context of hepatocellular cancer...

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PMID: 33182805
DOI: 10.3390/ijms21228452

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