Article
Compromised chitin synthesis in lager yeast affects its Congo red resistance and release of mannoproteins from the cells.
FEMS microbiology letters - 14 Dec 2020
Omura Fumihiko, Takagi Motoshige, Kodama Yukiko
Abstract excerpt
A mutant lager strain resistant to the cell wall-perturbing agent Congo red (CR) was isolated and the genetic alterations underlying CR resistance were investigated by whole genome sequencing. The parental lager strain was found to contain three distinct Saccharomyces cerevisiae (Sc)-type CHS6 (CHitin Synthase-related 6) alleles, two of which have one or two nonsense mutations in the open reading frame, leaving...
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