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Higher Increase in Plasma DHA in Females Compared to Males Following EPA Supplementation May Be Influenced by a Polymorphism in ELOVL2: An Exploratory Study.

Lipids - 1 Mar 2021

Metherel Adam H, Irfan Maha, Klingel Shannon L, Mutch David M, Bazinet Richard P

Abstract excerpt

Young adult females have higher blood docosahexaenoic acid (DHA), 22:6n-3 levels than males, and this is believed to be due to higher DHA synthesis rates, although DHA may also accumulate due to a longer half-life or a combination of both. However, sex differences in blood fatty acid responses to eicosapentaenoic acid (EPA), 20:5n-3 or DHA supplementation have not been fully investigated. In this exploratory...

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PMID: 33174255
DOI: 10.1002/lipd.12291

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