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Article

DHA intake interacts with ELOVL2 and ELOVL5 genetic variants to influence polyunsaturated fatty acids in human milk

26 Mar 2019

Abstract excerpt

Endogenous synthesis of PUFAs is mediated by genes controlling fatty acid elongases 2 and 5 ( ELOVL2 and ELOVL5 ) and by exogenous DHA intake. Associations between elongases and PUFA levels probably involve genetic variants of ELOVL and changes in DHA intake, but data about their combined effect on PUFA levels are sparse. We hypothesized that each factor would directly affect PUFAs and that interactions between...

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PMID: 30914501
DOI: 10.1194/jlr.m090951

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