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Article

Both maternal and offspring Elovl2 genotypes determine systemic DHA levels in perinatal mice.

Journal of lipid research - 1 Jan 2017

Pauter Anna M, Trattner Sofia, Gonzalez-Bengtsson Amanda, Talamonti Emanuela, Asadi Abolfazl, Dethlefsen Olga, Jacobsson Anders

Abstract excerpt

The molecular details relevant to dietary supplementation of the omega-3 fatty acid DHA in mothers as well as in their offspring are not clear. The PUFA elongase, elongation of very long-chain fatty acid (ELOVL)2, is a critical enzyme in the formation of DHA in mammals. In order to address the question regarding the origin of DHA during perinatal life, we have used DHA-deficient Elovl2-ablated mice as a model...

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Identifiers

PMID: 27864326
DOI: 10.1194/jlr.M070862
PMCID: PMC5234714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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